20 بهمن 1401
مريم مهاجراني

مریم مهاجرانی

مرتبه علمی: دانشیار
نشانی: بابلسر، پردیس دانشگاه مازندران، دانشکده علوم پایه، گروه زیست شناسی سلولی و مولکولی، کدپستی 95447-47416
تحصیلات: دکترای تخصصی / بیوشیمی
تلفن: 01135302455
دانشکده: دانشکده علوم پایه

مشخصات پژوهش

عنوان Amidofluorene-appended lower rim 1,3-diconjugate of calix[4]arene: synthesis, characterization and highly selective sensor for Cu2+
نوع پژوهش مقاله چاپ شده
کلیدواژه‌ها
calix[4]arene; chemosensor; copper ions; fluorene; fluorescence
مجله Beilstein Journal of Organic Chemistry
شناسه DOI doi:10.3762/bjoc.12.163
پژوهشگران رحمان حسین زاده (نفر اول) ، محمد نعمتی (نفر دوم) ، رضا زادمرد (نفر سوم) ، مریم مهاجرانی (نفر چهارم)

چکیده

Functionalization of calix[4]arene with amidofluorene moieties at the lower rim led to formation of the 1,3-diconjugate of calix[4]arene L as a novel fluorescent chemosensor for Cu2+. The receptor molecule L exhibited a pronounced selectivity towards Cu2+ over other mono and divalent ions. The formation of the complex between L and Cu2+ was evaluated by absorption, fluorescence and 1H NMR spectroscopy. The sensor L showed a remarkable color change from colorless to purple and a fluorescence quenching only upon interaction with Cu2+. The 1:1 stoichiometry of the obtained complex has been determined by Job’s plot. The association constant determined by fluorescence titration was found to be 1.8 × 106 M−1. The sensor showed a linear response toward Cu2+ in the concentration range from 1 to 10 μM with a detection limit of 9.6 × 10−8 M.