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Title Reductive amination of aldehydes and ketones to their corresponding amines with N-methylpyrrolidine zinc borohydride
Type JournalPaper
Keywords Aldehydes Ketones Reductive amination Amines N-Methylpyrrolidine zinc borohydride
Abstract A simple and convenient procedure for reductive amination of aldehydes and ketones using N-methylpyrrolidine zinc borohydride (ZBHNMP) as a reducing agent is described. The reactions are carried out with 1 equiv of amine and 1 equiv of aldehyde or ketone using 1 equiv of ZBHNMP in methanol under neutral conditions at room temperature.
Researchers Kazem Fazli (Fourth Researcher), Fatemeh Salehian (Third Researcher), mahmood tajbakhsh (Second Researcher), Heshmatollah Alinezhad (First Researcher)