2024 : 11 : 21
mahmood tajbakhsh

mahmood tajbakhsh

Academic rank: Professor
ORCID:
Education: PhD.
ScopusId:
HIndex:
Faculty: Faculty of Chemistry
Address: /Faculty of chemistry- University of Mazandaran- Babolsar- Iran
Phone: 09111146981

Research

Title
Antibacterial and cytotoxic effects of cyclodextrin-triazole-titanium based nanocomposite
Type
JournalPaper
Keywords
TiO2, Triazole, β-Cyclodextrin, antibacterial, cytotoxicity
Year
2021
Journal BRAZILIAN ARCHIVES OF BIOLOGY AND TECHNOLOGY
DOI
Researchers Zari Fallah ، Hossein Nasr Isfahani ، mahmood tajbakhsh ، Mojtaba Mohseni ، Ebrahim Zabihi ، zeinab abedian

Abstract

In this paper, the antibacterial activity of triazole functionalized cyclodextrin (CD.Click) and cyclodextrin-triazole-titanium based nanocomposite (CD.COM) was evaluated. The results indicated that CD.Click and CD.COM perform a wide range of antibacterial activity against both gram positive (Staphylococcus aureus and Bacillus subtilis) and gram negative (Escherichia coli and Pseudomonas aeruginosa) bacteria. The cytotoxic effect of CD.COM was investigated in vitro on cancerous cell lines (cervical cancer, breast carcinoma and sarcoma osteogenic) and fibroblast cells by MTT assay. The cell viability evaluation confirmed that the growth of cancerous cells.