2024 : 7 : 23
mahmood tajbakhsh

mahmood tajbakhsh

Academic rank: Professor
ORCID:
Education: PhD.
ScopusId:
Faculty: Faculty of Chemistry
Address: /Faculty of chemistry- University of Mazandaran- Babolsar- Iran
Phone: 09111146981

Research

Title
Safe and Efficient Reductive Methylation of Primary and Secondary Amines Using N-Methylpyrrolidine Zinc Borohydride
Type
JournalPaper
Keywords
Amine; formaldehyde; reductive methylation; ZBHNMP
Year
2010
Journal Synthetic Communications
DOI
Researchers Heshmatollah Alinezhad ، mahmood tajbakhsh ، Fatemeh Salehian ، Kazem Fazli

Abstract

An efficient, general procedure for reductive methylation of primary and secondary amines with 37% formaldehyde using N-methylpyrrolidine zinc borohydride (ZBHNMP) as a reducing agent gave the corresponding tertiary amines in excellent yields. The reaction was carried out in tetrahydrofuran under neutral conditions at 0–10 C