1403/03/31
محمود تاجبخش

محمود تاجبخش

مرتبه علمی: استاد
ارکید:
تحصیلات: دکترای تخصصی
اسکاپوس:
دانشکده: دانشکده شیمی
نشانی:
تلفن: 09111146981

مشخصات پژوهش

عنوان
Nano silica‑bonded aminoethylpiperazine: a highly efficient and reusable heterogeneous catalyst for the synthesis of 4H‑chromene and 12H‑chromeno[2,3‑d]pyrimidine derivatives
نوع پژوهش
JournalPaper
کلیدواژه‌ها
Nano silica, Aminoethylpiperazine, Basic catalyst, Chromene
سال
2015
مجله Journal of the Iranian Chemical Society
شناسه DOI
پژوهشگران mahmood tajbakhsh ، Mohadeseh Kariminasab ، Heshmatollah Alinezhad ، Rahman Hosseinzadeh ، Parizad Rezaei ، Mahgol Tajbakhsh ، Helia Janatian Gazvini ، Mohammadreza Azizi Amiri

چکیده

The reaction of nano silica with 3-chloro-propyltrimethoxysilane followed by treatment with ami-noethylpiperazine afforded nano silica-bonded aminoeth-ylpiperazine (SB-APP). The structure of the synthesized SB-APP was characterized by FT-IR, TGA, BET, SEM and elemental analysis and identified as an efficient basic catalyst for the preparation of 2-amino-4H-chromenes and 12H-chromeno[2,3-d]pyrimidine derivatives. One-pot three-component reaction of phenols, aromatic alde-hydes and malononitrile in the presence of the catalytic amounts of SB-APP afforded high yield of the correspond-ing 2-amino-4H-chromenes under mild reaction condi-tions. 12H-Chromeno[2,3-d]pyrimidines were successfully synthesized with reasonable yield by reacting the 2-amino-4H-chromenes with acetic anhydride in the same pot with-out purification of the corresponding chromene intermedi-ates. All products were characterized by FT-IR, 1H NMR, 13C NMR and MS data. The catalyst was simply recovered from the reaction mixture and reused several times without significant loss of catalytic activity.