and phylogenetic studies due to its particular features over the nuclear genome, consisting of the high mutation rate, the maternal mode of inheritance with non-recombination characteristics and the high copy number in each somatic cell. We have reported 45 haplotypes 3 and 121 variable sites from combined HVI, HVII and HVIII regions (D-loop). We established an estimate of high genetic diversity of 0.9870; a sufficiently Low random match probability of 0.0294 and a higher power of discrimination of 0.9703 when combined HVI, HVII and HVIII data were analyzed. These findings indicate the potential of mtDNA polymorphisms and haplotypes which can be utilized in forensic examinations to discriminate Indian Muslim individuals especially when nuclear DNA cannot be analyzed. The results of the present study demonstrate that the maternal genetic structure of Muslim population of South India Which it indicates that the mtDNA macrohaplogroup M is present in the Indo- Muslims at a frequency of 52% and macrohaplogroup N at a frequency of 48 %. It confirms that the Muslim population of South India displays a heterogeneous origin, with a high percentage of South Asian haplogroups followed by haplogroups to west Eurasia. To determine the effect of evolutionary forces two different analyses were computed that may be acting on population in this study, such as Tajima’s D, Fu’s Fs. The overall conclusion is that our target population is undergoing expansion. we sincerely hope that the population data generated will useful to interpret results of mtDNA sequence analyses in forensic work executed in the laboratories of India and it can be utilized in matrilineal or geographic origin research, as well as for further anthropological studies in India.
