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Seyed Reza Nabavi

Seyed Reza Nabavi

Academic rank: Associate Professor
ORCID: 0000-0002-2605-6710
Education: PhD.
ScopusId: 35213806100
HIndex:
Faculty: Faculty of Chemistry
Address: Department of Applied Chemistry, University of Mazandaran, Babolsar, Iran
Phone: 01135302397

Research

Title
Green Synthesis of Sulfur- and Nitrogen-Doped Carbon Quantum Dots for Determination of L-DOPA Using Fluorescence Spectroscopy and a Smartphone-Based Fluorimeter
Type
JournalPaper
Keywords
Carbon Quantum Dots, Green Synthesis, Levodopa, Optical Sensor
Year
2023
Journal ACS Omega
DOI
Researchers Amir Hemmati ، Hamid Emadi ، Seyed Reza Nabavi

Abstract

Sulfur- and nitrogen-doped carbon quantum dots (S,N-CQDs) were synthesized using feijoa leaves as a green precursor via a novel route. Spectroscopic and microscopic methods such as X-ray photoelectron spectroscopy, fluorescence spectroscopy, and high-resolution transmission electron microscopy were used to analyze the synthesized materials. The blue emissive S,N-CQDs were applied for qualitative and quantitative determination of levodopa (L-DOPA) in aqueous environmental and real samples. Human blood serum and urine were used as real samples with good recovery of 98.4–104.6 and 97.3–104.3%, respectively. A smartphone-based fluorimeter device was employed as a novel and user-friendly self-product device for pictorial determination of L-DOPA. Bacterial cellulose nanopaper (BC) was used as a substrate for S,N-CQDs to make an optical nanopaper-based sensor for L-DOPA determination. The S,N-CQDs demonstrated good selectivity and sensitivity. The interaction of L-DOPA with the functional groups of the S,N-CQDs via the photo-induced electron transfer (PET) mechanism quenched the fluorescence of S,N-CQDs. The PET process was studied using fluorescence lifetime decay, which confirmed the dynamic quenching of S,N-CQD fluorescence. The limit of detection (LOD) of S,N-CQDs in aqueous solution and the nanopaper-based sensor was 0.45 μM in the concentration range of 1–50 μM and 31.05 μM in the concentration range of 1–250 μM, respectively.