In this study, the nano NaY zeolite-supported metformin (YZ/PS/Met) was synthesized as an environmentally friendly and reusable nanocatalyst through the postmodifcation of the nano NaY zeolite (YZ) with 3-chloropropyl trimethoxysilane (CPTMS) followed by reaction with metformin (Met). The metformin-functionalized nano NaY zeolite (YZ/PS/Met) was characterized by various techniques, such as Fourier transform infrared spectroscopy (FT-IR), X-ray difraction (XRD), Dynamic light scattering (DLS), Thermal gravimetric analysis (TGA), Field emission scanning electron microscopy (FESEM), energy-dispersive X-ray spectroscopy (EDS), Brauer-emmett-teller (BET), t-plot, and elemental analyses. Then, the synthesizing of 2-amino-4H-chromenes was chosen to study the catalytic activity of (YZ/PS/Met), which aforded good to excellent yields (81–98%), short reaction times, at room temperature, and in green solvent (EtOH). The catalyst can be easily removed from the reaction media and reused up to seven consecutive times without signifcant reduction in catalyst performance. The nature of the attached metformin (Met) onto the NaY surface increased the catalytic activity and provided more homogeneity to the catalyst in the reaction media. Easy recovery and reuse of catalyst, simple product separation from the reaction mixture and generality of the method, easy handling, low catalyst cost, and mild reaction conditions make this approach an eco-friendly procedure for synthesizing the chromenes. The obtained results demonstrated that the presented catalytic procedure could be efective in the synthesis of other useful products under green reaction conditions.
