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َAbdolraouf Samadi-Maybodi

Academic rank: Professor
ORCID:
Education: PhD.
ScopusId:
Faculty: Faculty of Chemistry
Address:
Phone: 011-35302396

Research

Title
Trace analysis of N-acetyl-L-cysteine using luminol–H2O2 chemiluminescence system catalyzed by silver nanoparticles
Type
JournalPaper
Keywords
N-acetyl-L-cysteine; silver nanoparticles; luminol; chemiluminescence; pharmaceutical tablet
Year
2015
Journal LUMINESCENCE
DOI
Researchers َAbdolraouf Samadi-Maybodi ، Reza Akhoondi

Abstract

N-Acetyl-L-cysteine (NAC) can inhibit the luminol–H2O2, reaction, which is catalyzed by silver nanoparticles. Based on this phenomenon a new method was developed for NAC determination. Under optimum conditions, a linear relationship between chemiluminescence intensity and NAC concentration was found in the range 0.034–0.98 μg/mL. The detection limit was 0.010 μg/mL (S/N =3), and the relative standard deviation (RSD) was <5% for 0.480 μg/mL NAC (n =5). This simple, sensitive and inexpensive method has been applied to measure the concentration of NAC in pharmaceutical tablets. Copyright © 2014 John Wiley & Sons, Ltd.