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Rahman Hosseinzadeh

Rahman Hosseinzadeh

Academic rank: Professor
ORCID:
Education: PhD.
ScopusId:
Faculty: Faculty of Chemistry
Address: Department of Organic Chemistry, Faculty of Chemistry, University of Mazandaran, Babolsar, Iran
Phone: 01135302356

Research

Title
Preparation of Cu(OAc)<sub>2</sub>/MCM‐41 catalyst and its application in the one‐pot synthesis of 1,2,3‐triazoles in water
Type
JournalPaper
Keywords
1,2,3-triazoles; one-pot synthesis; Cu(OAc)2/MCM-41, catalyst
Year
2012
Journal Heteroatom Chemistry
DOI
Researchers Rahman Hosseinzadeh ، Hamid Sepehrian ، Farshid Shahrokhi

Abstract

An efficient one-pot synthesis of 1,2,3- triazoles via the three-component coupling reaction between benzyl or alkyl bromides, terminal alkynes, and sodium azide in the presence of catalytic amounts of Cu(OAc)2/MCM-41 catalyst has been described. This catalyst showed high catalytic activity and 1,4- regioselectivity for the [3 + 2]Huisgen cycloaddition. This method avoids isolation and handling of organic azides, using water as a solvent, and catalyst recycling makes this synthesis a truly green procedure.