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Rahman Hosseinzadeh

Rahman Hosseinzadeh

Academic rank: Professor
ORCID:
Education: PhD.
ScopusId:
Faculty: Faculty of Chemistry
Address: Department of Organic Chemistry, Faculty of Chemistry, University of Mazandaran, Babolsar, Iran
Phone: 01135302356

Research

Title
Application of a Modified Carbon Paste Electrode Using Core–Shell Magnetic Nanoparticle and Modifier for Simultaneous Determination of Norepinephrine, Acetaminophen and Tryptophan
Type
JournalPaper
Keywords
norepinephrine, acetaminophen, tryptophan, voltammetry, magnetic core-shell manganese ferrite nanoparticles, drug analysis
Year
2021
Journal RUSSIAN JOURNAL OF ELECTROCHEMISTRY
DOI
Researchers Sayed Zia Mohammadi ، Hadi Beitollahi ، Maryam Askari ، Rahman Hosseinzadeh

Abstract

The current study was conducted to synthesize 2-(4-ferrocenyl-[1,2,3]triazol-1-yl)-1-(naphthalen-2-yl) ethanone (2FTNE) as a mediator and magnetic core–shell manganese ferrite nanoparticles (CMNP) as a nanoparticle for construction of a modified carbon paste electrode (CPE). The electrochemical behavior of norepinephrine (NEP) was assessed using cyclic voltammetry and its determination was done by using differential pulse voltammetry (DPV) in the presence of tryptophan (TRP) and acetaminophen (AC). The 2FTNECMNP-modified CPE (2FTNECMNPPE) in comparison with bare CPE and CMNP modified CPE exhibited high electro-catalytic activity to the NEP oxidation. Linearity of the oxidation peak current with concentration of NEP was maintained between 0.075–60 μM (R2 = 0.9995). Limit of detection for NEP was obtained 0.016 μM on the basis of three times of standard deviation (3Sb) of blank. High selectivity, proper stability and suitable reproducibility are some advantages of the 2FTNECMNPPE that was successful in the measurement of NEP, AC and TRP in NEP ampoule, acetaminophen tablet and urine samples.