The behaviors of barrier characteristics and fusion cross sections are analyzed by changing neutrons over a wide range of colliding systems. For this purpose, we have extended our previous study [Ghodsi and Gharaei, Eur. Phys. J. A 48, 21 (2012), it is devoted to the colliding systems with neutron-rich nuclei] to 125 isotopic systems with the condition of 0.5 N/Z 1.6 for their compound nuclei. The AW 95, Bass 80, Denisov DP, and Prox. 2010 potentials are used to calculate the nuclear part of the interacting potential. The obtained results show that the trend of barrier heights VB and positions RB as well as nuclear VN and Coulomb VC potentials (at R = RB) as a function of (N/Z − 1) quantity are nonlinear (second order) whereas the fusion cross sections follow a linear dependence.