The genus Cyclotrichium includes nine species that are mainly distributed in Turkey, Lebanon, Iraq, and Iran, and are used in the kitchen, and also in complementary medicine to treat various diseases. During recent years, considerable progress has been made in analyzing their phytochemical composition in parallel with their antimicrobial properties and their therapeutic potentials. This study reviews the present knowledge about investigations on antimicrobial, insecticidal, and anticancer properties of the essential oils and any other purified chemical compounds of the Cyclotrichium species. Various phytochemicals have been isolated from the extracts of the plants of this genus having significant biological and therapeutic potentials. In conclusion, these gathered data strongly support the viewpoint that the species belonging to the genus Cyclotrichium have various biological and pharmaceutical activities to treat various diseases including cancer in addition to the remarkable antimicrobial and insecticidal potential with no or minimal health and environmental hazards.
