In this paper, fractional derivatives in the sense of modified Riemann-Liouville derivative and first integral method are applied for constructing exact solutions of nonlinear fractional generalized reaction duffing model and non- linear fractional diffusion reaction equation with quadratic and cubic nonlinearity. Our approach provides first integrals in polynomial form with a high accuracy for two-dimensional plane autonomous systems. Exact soliton solutions are con- structed through established first integrals