"Interpretation (Taʼwīl)" is one of the key topics in Quranic literature that has had significant importance and a special place in the fields of religious knowledge. To study and understand the Holy Quran correctly, research and investigation on this subject are necessary. The extent of Sayyid Murtaḍā's knowledge and the value of his works have led many researchers to consider his perspectives and works as subjects of their own scientific research. The present study aims, using a descriptive-analytical method, to examine interpretation in the Quranic thought of Sayyid Murtaḍā through. The research approach shows that Sayyid Murtaḍā introduced interpretation in the field of exegesis; it has general (ʻĀm) meaning which encompass exegesis. Therefore, when explaining the clear (Muḥkam) verses and also explaining the unclear (Mutashābih) verses, he used the term interpretation (Taʼwīl). According to him, there is a difference between the credibility of interpretation (proof of possible aspects) and the correctness of interpretation. His exegesis is in line with scientific and rational principles and he has a scholarly understanding of the Quran. His beliefs include belief in the divine nature of the Quranic words, belief in the comprehensibility of the Quran, affirmation of the truths in the words and expressions of the Quran, and the discovery of reasonable meanings attributable to God in the unclear (Mutashābih) verses, among others. The result of this research is beneficial for understanding the Quranic views of Sayyid Murtaḍā and benefiting from his experiences and skills in Quran exegesis; also, it addresses the need for a comprehensive approach to interpreting unclear and difficult verses.