1403/01/10
جهانبخش رئوف

جهانبخش رئوف

مرتبه علمی: استاد
ارکید:
تحصیلات: دکترای تخصصی
اسکاپوس:
دانشکده: دانشکده شیمی
نشانی:
تلفن: 01135302392

مشخصات پژوهش

عنوان
A high sensitive electrochemical nanosensor for simultaneous determination of glutathione, NADH and folic acid
نوع پژوهش
JournalPaper
کلیدواژه‌ها
Glutathione; NADH; Folic acid; ZnO/CNTs nanocomposite; Sensor
سال
2015
مجله Materials Science and Engineering C
شناسه DOI
پژوهشگران Jahan Bakhsh Raoof ، Nader Teymoori ، Mohammad Ali Khalilzadeh ، Reza Ojani

چکیده

In the present study, we report electrosynthesis of 4,5-bis(4-chloroanilino)-1,2-benzendiol (BCB) and its application as a selective electrochemical mediator at a surface of carbon paste electrode (CPE) modified ZnO/CNTs nanocomposite as a simple and rapid voltammetric sensor. The sensor showed an efficient catalytic activity for the electro-oxidation of glutathione (GSH), which leads to a lowered overpotential by more than 203 mV compared to unmodified carbon paste electrode. For the mixture containing GSH, nicotinamide adenine dinucleotide (NADH) and folic acid (FA), the electrooxidation signals were well separated. The square wave voltammetry (SWV) currents increased linearly with their concentration at the ranges of 0.006–161, 1.0–650 and 3.0–700μM, respectively with the detection limits of 0.002, 0.3 and 1.0μM. Finally, the electrode was successfully applied for the voltammetric determination of analytes in real samples with satisfactory results.