1403/01/09
جهانبخش رئوف

جهانبخش رئوف

مرتبه علمی: استاد
ارکید:
تحصیلات: دکترای تخصصی
اسکاپوس:
دانشکده: دانشکده شیمی
نشانی:
تلفن: 01135302392

مشخصات پژوهش

عنوان
Designing a novel DNA-based electrochemical biosensor to determine of Ba2+ ions both selectively and sensitively
نوع پژوهش
JournalPaper
کلیدواژه‌ها
Ba2+ ions; DNA-based biosensor; Carmoisine; Modified carbon paste electrode.
سال
2022
مجله ANALYTICAL BIOCHEMISTRY
شناسه DOI
پژوهشگران Nastran Ebrahimi ، Jahan Bakhsh Raoof ، Reza Ojani ، Maryam Ebrahimi

چکیده

This work describes a novel electrochemical biosensor based on G-quadruplex (G4) DNA for the sensitive and selective detection of Ba2+ ions using a Carbon Paste Electrode modified with Ag nanoparticles incorporated in reduced Graphene Oxide via a simple wet chemical method (Ag-rGO/CPE), in the presence of carmoisine (CA) as a new electrochemical indicator. The peak current of CA increased with increasing Ba2+ ions concentration and the DNA-based sensor showed linear ranges of 0.06-0.80 nM and 1.0-80 nM and a Limit of Detection (LOD) of 0.045 nM. The proposed biosensor showed a good selectivity toward Ba2+ ions in the presence of other metal ions such as Ag+, Hg2+, K+ and Na+ and was applied to the analysis of natural samples showing appropriate results.