Carboxymethyl Chitosan (CMCh) is a semi-synthetic derivative of chitosan (a natural biopolymer) with
increasing biomedical applications as a matrix or scaffold material for tissue engineering applications.
Since, the presence of impurities can cause immunological reactions in vivo where ultimately pure
materials are needed. To this end, purity of commercial-grade CMCh samples was investigated here along
with their purification by a solvent/nonsolvent technique. The resulting polymer was characterized by
differential scanning calorimetry (DSC), thermal gravimetric analysis (TGA), Fourier transform infrared
spectroscopy (FTIR) and energy dispersive X-ray spectroscopy (EDX) to confirm the validity of the
purification process.