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Heshmatollah Alinezhad

Heshmatollah Alinezhad

Academic rank: Professor
ORCID:
Education: PhD.
ScopusId:
Faculty: Faculty of Chemistry
Address:
Phone: 9111144735

Research

Title
Synthesis of novel 1,2,3-triazole derivatives of 2,3-dihydroquinazolin-4(1H)-one
Type
JournalPaper
Keywords
Quinazolin-4(1H)-one  1, 2, 3-Triazole  Click chemistry  Isatoic anhydride
Year
2016
Journal MONATSHEFTE FUR CHEMIE
DOI
Researchers Mohammad Mahdavi ، Mina Saeedi ، Maryam Karimi ، Niloufar Foroughi ، Fatemeh Hasanshahi ، Heshmatollah Alinezhad ، Alireza Foroumadi ، Abbas Shafiee ، Tahmineh Akbarzadeh

Abstract

This work reports an efficient route for the synthesis of novel 1,2,3-triazole derivatives of 2,3-dihydroquinazolin- 4(1H)-one starting from isatoic anhydride via a three-step reaction. The resulting 2-amino-N-substituted benzamides from the reaction of isatoic anhydride and benzylamines underwent coupling cyclization reaction with 4-(prop-2-yn-1-yloxy)benzaldehyde, and then click reaction with in situ prepared organic azides afforded the title compounds in good yields.