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Heshmatollah Alinezhad

Heshmatollah Alinezhad

Academic rank: Professor
ORCID:
Education: PhD.
ScopusId:
Faculty: Faculty of Chemistry
Address:
Phone: 9111144735

Research

Title
Synthesis of Novel Benzo[6,7][1,4]oxazepino[4,5-a]quinazolinone Derivatives via Transition-Metal-Free Intramolecular Hydroamination
Type
JournalPaper
Keywords
hydroamination, 2-aminobenzamides, terminal alkynes, 7-exo-dig, N-heterocycles
Year
2014
Journal SYNLETT
DOI
Researchers Mohammad Mahdavi ، Niloufar Foroughi ، Mina Saeedi ، Maryam Karimi ، Heshmatollah Alinezhad ، Alireza Foroumadi ، Abbas Shafiee ، Tahmineh Akbarzadeh

Abstract

Novel benzo[6,7][1,4]oxazepino[4,5-a]quinazolinone derivatives were synthesized through an efficient 7-exo-dig hydroamination of 3-substituted-2-[2-(prop-2-yn-1-yloxy)phenyl]- 2,3-dihydroquinazolin-4(1H)-ones in the presence of potassium tert-butoxide (KOt-Bu) in DMF at 130 °C.