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Heshmatollah Alinezhad

Heshmatollah Alinezhad

Academic rank: Professor
ORCID:
Education: PhD.
ScopusId:
Faculty: Faculty of Chemistry
Address:
Phone: 9111144735

Research

Title
Efficient synthesis of novel benzo [f]imidazo[1,2-d] [1,4]oxazepine-5(6H)-one derivatives
Type
JournalPaper
Keywords
Oxazepine  1,2-Diketones  Ammonium acetate  2-Formyl phenoxy acetic acid  Cyclization
Year
2017
Journal RESEARCH ON CHEMICAL INTERMEDIATES
DOI
Researchers Hossein Yavari ، Heshmatollah Alinezhad ، mahmood tajbakhsh

Abstract

A convenient and efficient method is described for the synthesis of novel tricyclic scaffolds incorporating an imidazole ring and medium-sized benzoxazepine ring, via the reaction of 1,2-diketons, 2-formyl phenoxy acetic acids and ammonium acetate in acetic acid under reflux conditions, and then the addition of thionyl chloride to produce lactam in the absence of a catalyst.