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Heshmatollah Alinezhad

Heshmatollah Alinezhad

Academic rank: Professor
ORCID:
Education: PhD.
ScopusId:
Faculty: Faculty of Chemistry
Address:
Phone: 9111144735

Research

Title
Facile method for the synthesis of 2,3- dihydroquinazolin-4(1H)-ones catalyzed by SiO2–H3PW12O40 in water
Type
JournalPaper
Keywords
2,3-Dihydroquinazolin-4(1H)-one  SiO2–H3PW12O40  2-Aminobenzamide  Heterogeneous catalyst
Year
2017
Journal RESEARCH ON CHEMICAL INTERMEDIATES
DOI
Researchers Heshmatollah Alinezhad ، Elham Solymani ، Mahboobeh Zare

Abstract

The 12-tungstophosphoric acid supported on silica gel (PW/SiO2) exhibits excellent activity in the synthesis of 2,3-dihydroquinazolin-4(1H)-ones by cyclocondensation reaction of 2-aminobenzamide with carbonyl compounds in water under reflux conditions. The desired products have been obtained in short reaction times in high yields. Our method has been successfully applied for both aldehydes and ketones (aromatic and aliphatic). Easy recovery and reusable catalyst, easy work-up and avoidance of using harmful organic solvents are the major advantages of our method in comparison to existing methods.