We report a method to obtain biocompatible PEG copolymer coatings inside high density polyethylene and Pyrex tubes, which was successfully developed by using a transporting discharge. The latter being a dry process, it is easier to apply as compared to the conventional multistep wet chemical techniques. The results presented in this paper show that for a 70 cm tube good cell repellent properties as compared to the control was obtained for the entire length of the tube. The best nonfouling properties with respect to CT-26 (colon cancer) were obtained for coatings presenting the best retention of ether functionalities from the DEGME monomer i.e. between 5 and 25 cm downstream of the tube. These results are interesting for surface modification of biomaterial and biomedical devices, which present hollow bodies.