1403/01/09

رضا اوجانی

مرتبه علمی: استاد
ارکید:
تحصیلات: دکترای تخصصی
اسکاپوس:
دانشکده: دانشکده شیمی
نشانی:
تلفن: 011 35302350

مشخصات پژوهش

عنوان
Label-free electrochemical aptasensor for determination of chloramphenicol based on gold nanocubes-modified screen-printed gold electrode
نوع پژوهش
JournalPaper
کلیدواژه‌ها
Aptamer, Chloramphenicol, Gold nanocube, Aptasensor, Screen-printed gold electrode
سال
2015
مجله ELECTROANALYSIS
شناسه DOI
پژوهشگران Ayemeh Baghery Hashkavayi ، Jahan Bakhsh Raoof ، Reza Ojani ، Ezat Hamidi-Asl

چکیده

An ultrasensitive label-free electrochemical aptasensor was developed for selective detection of chloramphenicol (CAP). The aptasensor was made using screen-printed gold electrode modified with synthesized gold nano cube/cysteine. The interactions of CAP with aptamer were studied by cyclic voltammetry, square wave voltammetry (SWV) and electrochemical impedance spectroscopy. Under optimized conditions, two linear calibration curves were obtained for CAP determination using SWV technique, from 0.03 to 0.10 µM and 0.25– 6.0 µM with a detection limit of 4.0 nM. The aptasensor has the advantages of good selectivity and stability and applied to the determination of CAP in human blood serum sample.