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Robabeh Baharfar

Robabeh Baharfar

Academic rank: Professor
ORCID:
Education: PhD.
ScopusId:
Faculty: Faculty of Chemistry
Address:
Phone: 01135302358

Research

Title
Efficient one-pot synthesis of highly functionalized furan fused spirooxindoles using pyridinium salt
Type
Presentation
Keywords
multicomponent reaction, spirooxindole, isatin, 3-cyanoacetyl indole, N-phenacyl pyridinium bromide
Year
2017
Researchers Hashem Bagheri ، Robabeh Baharfar ، Razieh Azimi

Abstract

A facile and efficient approach for the synthesis of 2-benzoyl-5-(1H-indol-3-yl)-2'-oxo-2H-spiro[furan-3,3'-indoline]-4-carbonitrile derivatives was developed via a one-pot, three-component reaction of isatins with 3-cyanoacetyl indole and N-phenacylpyridinium bromide in the presence of triethylamine. the reaction was carried out in ethanol under reflux conditions, and the products were obtained in good to moderate yields with a simple work-up procedure.