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Robabeh Baharfar

Robabeh Baharfar

Academic rank: Professor
ORCID:
Education: PhD.
ScopusId:
Faculty: Faculty of Chemistry
Address:
Phone: 01135302358

Research

Title
Stereoselective Synthesis of Multifunctional Spirooxindole-Dihydrofuran Derivatives
Type
JournalPaper
Keywords
Isatin; multicomponent reaction; multifunctional spirooxindole-dihydrofurans; stereoselective synthesis
Year
2022
Journal POLYCYCLIC AROMATIC COMPOUNDS
DOI
Researchers Hashem Bagheri ، Robabeh Baharfar ، Razieh Azimi

Abstract

A facile and efficient protocol for the diastereoselective synthesis of novel spirooxindole-dihydrofurans has been developed by the three-component condensation of isatin derivatives, 3-cyanoacetyl indole, and N-phenacylpyridinium bromide in the presence of triethylamine base. The reaction was carried out in ethanol under reflux conditions, and various dihydrofuranyl spirooxindoles were obtained in high yields with good to excellent stereoselectivity