A number of nanoparticles have been developed and evaluated over the past few years. They have been found to have favorable properties in biology and medicine, making them effective carriers for the delivery of drugs and the stabilization of enzymes. The purpose of this study is to synthesize magnetic iron nanoparticles coated with alginate/PVA. Alginate has been investigated due to its biocompatibility, low toxicity, and relatively low cost. Further, the challenges associated with synthesized materials are discussed in terms of conclusions and future prospects. In this study, co-precipitation method was used in this study to synthesize alginate magnetic nanoparticles using FeCl2, FeCl3, and polyvinyl alcohol (PVA). Epichlorohydrin was used as a linker to connect alginate/PVA on the surface of magnetic nanoparticles during the synthesis process. As a final step, the reaction mixture was kept at 60 degrees Celsius for one hour, followed by washing and separation. Then, FTIR was used to investigate the formation of synthesized nanoparticles and the presence of functional groups related to these polymers and iron. Synthesized nanoparticles possess good magnetic properties, so an external magnet was able to separate them from the solution. As demonstrated by FTIR analysis, this nanoparticle was well formed with a coating consisting of alginate and PVA. Due to these findings, synthesizing magnetic iron nanoparticles coated with alginate/PVA in order to stabilize the enzyme will result in its stability and its reuse
