Furfuryl alcohol is an important platform chemical with a wide range of industrial applications. In this study, the optimization of operating parameters for the production of furfuryl alcohol in a reactive distillation column was investigated using response surface methodology (RSM). The key operating parameters, such as pressure, reflux ratio, feed ratio, and residence time, were examined to determine their influence on the yield of furfuryl alcohol. A Box–Behnken design (BBD) was employed to model the relationships between the process variables and the responses. The optimal operating conditions were determined by maximizing the furfuryl alcohol yield. The results showed that feed ratio and reflux ratio had the most significant impact on the process performance. The optimal operating conditions were found to be a pressure of 0.4 bar, reflux ratio of 5.6, feed ratio of 1, and residence time of 14. Under these conditions, the furfuryl alcohol yield is 99 %
