1403/01/10
علی اکبر عموئی

علی اکبر عموئی

مرتبه علمی: دانشیار
ارکید:
تحصیلات: دکترای تخصصی
اسکاپوس:
دانشکده: دانشکده مهندسی و فناوری
نشانی:
تلفن: 01135305105

مشخصات پژوهش

عنوان
A simple correlation to predict drug solubility in supercritical carbon dioxide
نوع پژوهش
JournalPaper
کلیدواژه‌ها
Carbon dioxide Drug solubility Correlatio
سال
2014
مجله FLUID PHASE EQUILIBRIA
شناسه DOI
پژوهشگران Ali Amoiee

چکیده

The availability of easy correlation of drug solubility in supercritical fluids without time-consuming calculations and difficult is crucially important for improvement of supercritical technology in pharmaceutical industries. This work proposes a new correlation to predict drugs solubility in CO2. The main advantages are its simplicity and minimal input data, namely temperature and density. The proposed drug solubility correlation in CO2has better performance (lower AARE%) respect to eight other empirical equations. Due to data sets, the mean AARE for the proposed model was 6.88%.