2024 : 11 : 1
Ali Bahari

Ali Bahari

Academic rank: Professor
ORCID:
Education: PhD.
ScopusId:
HIndex:
Faculty: Science
Address:
Phone: 9112537702

Research

Title
Magnetic Performance and Evaluation of Radiofrequency Hyperthermia of Perovskite La1−xSrxMnO3
Type
JournalPaper
Keywords
La1−xSrxMnO3 nanoparticles · Superparamagnetic · Cytotoxicity
Year
2018
Journal Journal of Superconductivity and Novel Magnetism
DOI
Researchers Shida Lotfi ، S. Bahari ، Ali Bahari ، Mandana Roodbari

Abstract

Magnetic nanoparticles (MNPs) can induce localized hyperthermia by alternating magnetic fields, in order to kill cells at tumor sites. In this study, La1−xSr x MnO3 nanoparticles with x = 0.2, 0.3, 0.4, and 0.5 were prepared via sol–gel technique. The synthesized nanoparticles were characterized in terms of structure, morphology, and magnetic properties with Fourier transform infrared (FTIR), X-ray diffraction (XRD), scanning electron microscopy (SEM), transmission electron microscopy (TEM), and vibrating sample magnetometer (VSM) studies. The average size of nanoparticles was measured to be 57.09, 30.477, 10.24, and 35.982 nm by Williamson–Hall method for x = 0.2, 0.3, 0.4, and 0.5, respectively. The absence of hysteresis in the magnetic response of nanoparticles represents the superparamagnetic behavior. Toxicity test was also performed to evaluate the toxicity concerns of the prepared nanoparticles upon entrance to the body. Furthermore, the alternating current magnetic heating characteristics of La1−xSr x MnO3 nanoparticles was also studied, by 1 mg/mL concentration, to test the ability of the nanoparticles as magnetic hyperthermia treatment agents. The magnetothermia were measured in an RF magnetic field of 88 Oe and 430 kHz. The present work reveals that LSMO nanoparticles possess the biocompatible properties for biomedical applications and can provide the required heat at appropriate time.