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Seyed Reza Nabavi

Seyed Reza Nabavi

Academic rank: Associate Professor
ORCID: 0000-0002-2605-6710
Education: PhD.
ScopusId: 35213806100
Faculty: Faculty of Chemistry
Address: Department of Applied Chemistry, University of Mazandaran, Babolsar, Iran
Phone: 01135302397

Research

Title
Synthesis of bioactive polyaniline-b-polyacrylic acid copolymer nanofibrils as an effective antibacterial and anticancer agent in cancer therapy, especially for HT29 treatment
Type
JournalPaper
Keywords
Bioactive polyaniline-b-polyacrylic acid copolymer, nanofibrils, antibacterial and anticancer agent, cancer therapy
Year
2020
Journal RSC Advances
DOI
Researchers nazanin bagheri ، Moslem Mansour Lakouraj ، Seyed Reza Nabavi ، Hamed Tashakkorian ، Mojtaba Mohseni

Abstract

In this work, a new highly water-soluble copolymer of polyacrylic acid with polyaniline is introduced. Acrylic acid was polymerized via the Reversible Addition Fragmentation Chain Transfer method (RAFT) in the presence of an initiator and the obtained polyacrylic acid was copolymerized with aniline at room temperature. As the main achievements of this work, the resulting block copolymer with nanosized structure revealed favorable solubility in polar solvents, as well as excellent antibacterial and anticancer activities. Therefore, it is an appropriate candidate for medical applications such as wound healing and cancer therapy, especially in HT29 treatment.