20 بهمن 1401
سلمان احمدي اسب چين

سلمان احمدی اسب چین

مرتبه علمی: دانشیار
نشانی: بابلسر، دانشکده علوم پایه
تحصیلات: دکترای تخصصی / میکروبیولوژی
تلفن: --
دانشکده: دانشکده علوم پایه

مشخصات پژوهش

عنوان Antagonistic Activity of Nocardia brasiliensis PTCC 1422 Against Isolated Enterobacteriaceae from Urinary Tract Infections
نوع پژوهش مقاله چاپ شده
کلیدواژه‌ها
Nocardia brasiliensis  Enterobacteriaceae  Urinary tract infections  Antagonistic activity
مجله Probiotics and Antimicrobial Proteins
شناسه DOI
پژوهشگران حسین کفشدار جلالی (نفر اول) ، عبدالرضا سلامت زاده (نفر دوم) ، آرزو کفشدار جلالی (نفر سوم) ، حامد حدادکاشانی (نفر چهارم) ، سلمان احمدی اسب چین (نفر پنجم) ، خسرو عیسی زاده (نفر ششم به بعد)

چکیده

The main drawback of current antibiotic therapies is the emergence and rapid increase in antibiotic resistance. Nocardiae are aerobic, Gram-positive, catalasepositive, non-motile actinomycetes. Nocardia brasiliensis was reported as antibiotic producer. The purpose of the study was to determine antibacterial activity of N. brasiliensis PTCC 1422 against isolated Enterobacteriaceae from urinary tract infections (UTIs). The common bacteria from UTIs were isolated from hospital samples. Antimicrobial susceptibility test was performed for the isolated pathogens using Kirby–Bauer disk diffusion method according to clinical and Laboratory Standards Institute guideline. Antagonistic activity of N. brasiliensis PTCC 1422 was examined with well diffusion methods. Supernatant of N. brasiliensis PTCC 1422 by submerged culture was analyzed with gas chromatography–mass spectrometry. Isolated strains included Escherichia coli, Klebsiella pneumoniae, Serratia marcescens and Proteus mirabilis. The most common pathogen isolated was E. coli (72.5 %). Bacterial isolates revealed the presence of high levels of antimicrobial resistances to ceftriaxone and low