1403/01/31
مجتبی محسنی

مجتبی محسنی

مرتبه علمی: دانشیار
ارکید: 0000-0002-5709-6600
تحصیلات: دکترای تخصصی
اسکاپوس: 55937730000
دانشکده: دانشکده علوم پایه
نشانی: بابلسر، پردیس دانشگاه مازندران، مجموعه علوم زیستی، گروه میکروبیولوژی
تلفن: +98-11-3530-2497

مشخصات پژوهش

عنوان
Synthesis of bioactive polyaniline-b-polyacrylic acid copolymer nanofibrils as an effective antibacterial and anticancer agent in cancer therapy, especially for HT29 treatment
نوع پژوهش
JournalPaper
کلیدواژه‌ها
Bioactive polyaniline-b-polyacrylic acid copolymer, nanofibrils, antibacterial and anticancer agent, cancer therapy
سال
2020
مجله RSC Advances
شناسه DOI
پژوهشگران nazanin bagheri ، Moslem Mansour Lakouraj ، Seyed Reza Nabavi ، Hamed Tashakkorian ، Mojtaba Mohseni

چکیده

In this work, a new highly water-soluble copolymer of polyacrylic acid with polyaniline is introduced. Acrylic acid was polymerized via the Reversible Addition Fragmentation Chain Transfer method (RAFT) in the presence of an initiator and the obtained polyacrylic acid was copolymerized with aniline at room temperature. As the main achievements of this work, the resulting block copolymer with nanosized structure revealed favorable solubility in polar solvents, as well as excellent antibacterial and anticancer activities. Therefore, it is an appropriate candidate for medical applications such as wound healing and cancer therapy, especially in HT29 treatment.