2024 : 4 : 29
Jahan Bakhsh Raoof

Jahan Bakhsh Raoof

Academic rank: Professor
ORCID:
Education: PhD.
ScopusId:
Faculty: Faculty of Chemistry
Address: Electroanalytical Chemistry Research Laboratory, Department of Analytical Chemistry, Faculty of Chemistry, University of Mazandaran, Babolsar, 47416-95447, Iran
Phone: 01135302392

Research

Title
Determination of Propranolol at a Carbon Paste Electrode Modified with Magnetite–Graphene Oxide in Combination with Presence of Sodium Dodecyl Sulfate Determination of Propranolol at a Carbon Paste Electrode Modified with Magnetite–Graphene Oxide in Combination with Presence of Sodium Dodecyl Sulfate
Type
JournalPaper
Keywords
propranolol, magnetite–graphene oxide, SDS, sensor, modified electrode
Year
2022
Journal Russian Journal of Electrochemistry
DOI
Researchers Hediyeh Bagheri Ladmakhi ، Fereshteh Chekin ، Shala Fathi ، Jahan Bakhsh Raoof

Abstract

In this study, a new electrochemical sensor based on magnetite graphene oxide/modified carbon paste electrode (Fe3O4–GO/CPE) was applied for determination of a cardiovascular drug, propranolol (PRO) in solution containing sodium dodecyl sulfate (SDS) as a surfactant. Results show that combination of modified electrode with surfactant addition, considerably increased electroanalytical signal for PRO determination and resulted to sensitive detection of PRO with linear range of 10–1500 μM, limit of detection of 4.5 μM and sensitivity of 166 μA mM–1. Applicability of this analytical method for detection of PRO in pharmaceutical formulations was studied and acceptable results obtained.