January 29, 2023
Abbass Ghanbabri-Niaki

Abbass Ghanbabri-Niaki

Degree: Professor
Education: Ph.D in Exercise Physiology
Phone: 01135302218
Faculty: Faculty of Physical Education and Sports Sciences


Title Short-term circuit resistance training improves insulin resistance probably via increasing circulating Adropin
Type Article
Circuit resistance training · Insulin resistance · Glucose metabolism · Adropin
Journal Journal of Diabetes and Metabolic Disorders
DOI 10.1007/s40200-022-01020-4
Researchers Najmeh Rezaeinezhad (First researcher) , Rostam Alizadeh (Second researcher) , Abbass Ghanbabri-Niaki (Third researcher)


Abstract Aim and background The underlying mechanism of exercise-induced insulin resistance (IR) improvement is unclear. Adropin is a multifunctional peptide has a significant role in the regulation of physical activity and insulin sensitivity. Thus, the aim of this study was to evaluate the effects of various circuit resistance (CRT) intensities on circulating adropin levels and IR and their relation. Method Forty-five voluntarily male men randomly were divided into 5 groups; control and 4 groups of CRT (20%, 40%, 60% and 80% of one-repetition maximum (1-RM)). Training groups performed CRT protocol 3 times a week for 6 weeks. Blood samples were drawn before and 48 h after the last training session and used for analyzing serum levels of adropin, glucose and insulin. Results The results showed that varying CRT intensities were associated with adropin elevation in comparison to the control group. Further analysis revealed that plasma adropin is higher in the 20% 1-RM group compared to the 40% 1-RM group. Furthermore, fasting insulin and glucose, as well as IR, were decreased in response to different CRT intensities. In addition, these reductions were significantly correlated with adropin level. Conclusion It can be speculated that different CRT intensities improve IR probably via increasing adropin level, and should be considered as an effective training method for diminishing glucose metabolism disorders.